📄 Category

public and global health

233 papers

Application of Discriminant Analysis for Blood Pressure Classification Based on Vital Signs: Evidence from a Regional Hospital in Ghana

This retrospective study of 1,000 adult patients at a Ghanaian regional hospital demonstrates that linear discriminant analysis using routinely collected vital signs, particularly body weight, can accurately classify patients into hypotensive, normotensive, or hypertensive categories, supporting the feasibility of data-driven risk stratification for cardiovascular and metabolic conditions.

Cobbinah, D., Addor, J. A., Narh, K. M. A. + 1 more2026-03-09📄 public and global health

The Emerging Dominance of Genetic Disorders in Under 5 Mortality: A Global Comparative Assessment and Frontier Analysis, 1990 to 2021

This study utilizes Global Burden of Disease 2021 data to reveal that while absolute mortality from genetic disorders in children under five has declined since 1990, their proportional contribution to deaths has nearly doubled, establishing them as a leading structural barrier to achieving SDG 3.2 and highlighting significant, often overlooked, opportunities for mortality reduction through improved screening and surgical care across all development levels.

Ruan, J., Tao, Z., Zhang, K. + 4 more2026-03-09📄 public and global health

Should We Keep Changing the Clock? Characterizing Causal Effects of Daylight Saving Time on Behavior and Physiology

Using large-scale, objective wearable data from the NIH All of Us Research Program, this study employs a causal difference-in-differences design to reveal that Daylight Saving Time transitions do not alter total daily activity but instead reallocate steps across the day, with these shifts varying significantly by age, income, and activity phenotype due to structural constraints.

Jeong, H., Katta, S., Wang, W. K. + 2 more2026-03-08📄 public and global health

COLLABORATIVE MAPPING AS A METHODOLOGY FOR IDENTIFYING COMMUNITY PERCEPTIONS ON BASIC SANITATION NEEDS AND INTERVENTIONS FOR LEPTOSPIROSIS IN SALVADOR, BRAZIL

This study demonstrates that collaborative mapping with residents of two peripheral communities in Salvador, Brazil, effectively identified specific local sanitation needs and intervention priorities—particularly regarding sewage and waste management near local rivers—that are essential for preventing leptospirosis, revealing a negative correlation between perceived intervention needs and predicted disease seropositivity.

Palma, F. A. G., Cuenca, P. R., de Oliveira, D. S. + 19 more2026-03-07📄 public and global health

Escalating burden and mortality of carbapenem-resistant Klebsiella pneumoniae species complex infections in Bangladeshi infants

An 18-year genomic epidemiology study in Bangladesh reveals a dramatic rise in carbapenem-resistant *Klebsiella pneumoniae* species complex infections among infants, driven by the emergence of high-risk clones like ST11, ST16, and ST147, which has led to a doubling of hospital case-fatality rates from 21.4% to 51.4% and underscores the urgent need for enhanced infection control, equitable access to effective therapies, and vaccine development.

Hooda, Y., Tanmoy, A. M., Kanon, N. + 25 more2026-03-06📄 public and global health

Deep untargeted wastewater metagenomic sequencing from sewersheds across the United States

This paper presents CASPER, the largest publicly available untargeted wastewater metagenomic dataset to date, comprising 1,206 deep-sequenced samples from across the United States that enable population-scale pathogen surveillance, correlation with clinical trends, and the detection of emerging viral threats like avian influenza and measles.

Justen, L. J., Rushford, C., Hershey, O. S. + 35 more2026-03-06📄 public and global health

Engaging communities through participatory learning action for the control and prevention of diabetes: a protocol for the Process Evaluation of the EMPOWER-D trial in Pakistan and Afghanistan

This paper outlines the protocol for a mixed-methods process evaluation of the EMPOWER-D trial, which aims to assess the implementation, mechanisms of impact, and contextual factors of a participatory learning and action intervention for preventing type 2 diabetes in community settings across Pakistan and Afghanistan.

Ishaq Khattak, M., Rehman, K., Afaq, S. + 7 more2026-03-06📄 public and global health

Hump nosed pit viper envenoming in Coastal Karnataka- unravelling the centuries of deadly camouflage

This retrospective study of 46 Hump-nosed pit viper envenomation cases in Coastal Karnataka characterizes the clinical syndrome and complications, notably venom-induced consumptive coagulopathy and acute kidney injury, while evaluating the limited efficacy of current treatments like antivenom and blood products to underscore the urgent need for a species-specific antivenom.

Wagle, U., Sirur, F. M., Lath, V. + 4 more2026-03-06📄 public and global health

Detection of viruses of public health importance in wastewater samples using conventional PCR techniques and a targeted enrichment whole genome sequencing panel.

This study demonstrates that combining conventional PCR/qPCR with a targeted enrichment whole-genome sequencing panel provides complementary and enhanced capabilities for detecting and characterizing a broad spectrum of public health viruses in wastewater surveillance.

Castro, G. M., Mallou, M. F., Masachessi, G. + 6 more2026-03-06📄 public and global health

Effectiveness of an automated text message intervention for weight management in postpartum women with overweight or obesity (Supporting MumS (SMS)): a UK wide, multicentre, two arm, parallel group, randomised controlled trial.

This UK-wide randomized controlled trial found that while a 12-month automated text message intervention did not significantly reduce weight in postpartum women with overweight or obesity compared to an active control group, it successfully improved dietary habits, physical activity levels, and infant feeding practices.

Gallagher, D., Spyreli, E., Calder-MacPhee, N. + 23 more2026-03-06📄 public and global health

"You become free, you can tell her anything": Perceptions of a peer-based medication delivery implementation strategy to improve hypertension medication adherence in western Kenya

This study in rural western Kenya utilized focus groups and interviews to assess stakeholder perceptions of a peer-based medication delivery and health information technology strategy for hypertension, revealing that while the approach is valued for improving access and psychosocial support, its success depends heavily on peer competency and communication.

Watiri, C., Wachira, J., Njuguna, B. + 8 more2026-03-06📄 public and global health

Effectiveness of health mediation to promote organized cancer screening among underserved and under-screened populations in Marseille, France: findings from a repeated cross-sectional survey

A repeated cross-sectional survey in Marseille demonstrates that a multicomponent health mediation program significantly increased breast and colorectal cancer screening uptake and awareness among exposed individuals in disadvantaged neighborhoods, although it did not produce a significant effect at the overall population level.

Legendre, E., Dutrey-Kaiser, A., Attalah, Y. + 11 more2026-03-06📄 public and global health

Management implications of shifting Culex quinquefasciatus West Nile virus transmission suitability in Florida

Projections indicate that climate change and urbanization will significantly extend the seasonal transmission suitability of West Nile virus by *Culex quinquefasciatus* in Florida, potentially exposing up to 70% of the state's population to year-round risk by 2050 and necessitating expanded vector control and public health resources.

Ryan, S. J., Lippi, C. A.2026-03-05📄 public and global health

Electrodermal Mapping of Sympathetic Activation Following Sleep Arousal Onset

This study utilizes high-resolution electrodermal activity recordings to demonstrate that sleep arousals trigger robust, sustained sympathetic sudomotor activation characterized by clustered bursts and amplitude enhancement, particularly in longer events, thereby establishing EDA as a sensitive and direct marker for quantifying sleep-related autonomic shifts.

Canbaz Gumussu, T., Posada-Quintero, H. F., Kong, Y. + 3 more2026-03-05📄 public and global health